Autophagy is a Critical Regulator of Memory CD8+ T Cell Formation

An Oxford University team has demonstrated that spermidine induces autophagy and  boosts older immune systems. This study shows that when elderly mice (corresponding to 90-year-old humans) are given spermidine and a vaccine together, the older mice have a better immune response than younger mice (corresponding to 20-year-old humans) who are also given a spermidine and vaccine cocktail.