Spermidine Protects Telomere Length

The inevitable process of aging leads to a decrease in cellular functions, which may lead to hair loss, neurodegeneration, and telomere attrition. Telomere attrition refers to the shortening of the telomeres, which may lead to an increased risk of heart and infectious diseases. 

A 6-month study in 2021 reveals that spermidine reduces telomere attrition. Older mice were administered spermidine, and results have revealed that age-associated phenotypes have notably decreased, leading to a decrease in age-induced hair loss and suppression of cardiac inflammation. The positive effects of spermidine were shown to be linked with the decrease of telomere attrition in mice.